Claim: DNA is a product of material, chemical processes with no evidence of being intelligently designed.
Response: DNA is a physical medium encoded with Complex Specified Information which prescribes the features and biochemistry of organisms.1 This verifies they are adenine, cytozine, guinine, or thymine, are able to bond to any of the binding sites of the ribose backbone of DNA. Therefore, chemical determinacy has not organized the nucleotides of DNA as information-bearing symbols.
Information is a non-material entity which cannot be produced by material processes.
Information is a product of intelligence.
Therefore, DNA is a product of intelligence and not material processes.
Since all organisms are prescribed by information, all organisms are a product of Intelligent Design.
The properties of genetic information which verify that DNA is impirical evidence of Intelligent Design are:
It has an intended purpose which has been preconceived - the process of forethought
The intended purpose is to cause the recipient to have an intended response
The intended response is to assemble proteins or regulate cell processes
The instructions to assemble proteins and regulate cell processes employ a coded language that both the sender (designer) and recipient (cell) understand
The instructions are organized syntaxically and grammatically so that the assembly or regulation occurs as specified and in a prescribed order
The end result is that the intended purpose is achieved
Intentionality, purpose, instruction, code, language, and forethought are mental processes, not material ones
The value of the information is it's meaning and purpose, not in a material quantity, such as the number of digits or characters in a sequence
Examples:
A pound of gold is of greater value that a pound of sand
A string of 9 unvarying characters such as "AAAAAAAAA" does not convey meaning. However, a string of 9 characters such as "TURN_LEFT" conveys meaning.
A varying string 19 of letters such as "AFGOPHRQLBNCMRIDAKX" does not convert convey meaning because no syntax or grammar (languge) is present. However, a varying string of only 9 characters such as "TURN_ONCE" conveys meaning because it is organized syntaxically and grammatically (linguistically)
Information is a non-material entity. It is not comprised of matter or a property of matter - it is not a material quantity such as mass or the number of digits or characters in a string
Material processes cannot produce that which is non-material
The intentional volition of the sender to convey knowledge is the origin of information
The sender creates information by mental processes which are non-material
Intentional volition and mental processes are properties of intelligence
The origin of information is intelligence
Conclusion: Since information is created by intelligence, and since all biological forms are prescribed by genetic information, the Intelligent Design of all biological forms is empirically demonstrated, and all theories of abiogenesis and the evolution of biological forms are empirically false.
Genetic information is a product of a mind.
It is prescriptive - it prescribes the structural design and biochemistry of organisms
It prescribes function of proteins by prescribing their structural design, which determines their functions and relationships with other proteins and cell structures
It prescribes organismal features, such as organs, their arrangement in a body plan, and their relationship to each other
It prescribes the regulation of information expression in time (4th dimension of genetic information) to maintain and operate an organism
It possesses a code system which is the alphabet of it's language system
It possesses linguistics properties - phonetics, semantics, punctuation, syntax, and grammar
Language is physically represented by symbols
Symbolism is non-material - symbols represent objects, processes, or concepts which are external to themselves
The application of meaning to a symbol and interpretation of meaning from a symbol is a mental process, not a material process.
Minds apply meaning to matter, not the other way around.
It is illogical to apply mental properties to matter
Information is a non-material entity
Information is purposeful - it describes something meaningful such as data, function, concept, or process.
Information cannot be physically measured because it has no physical dimensions or mass - the concept of measuring one pound or one meter of information is nonsensical.
Information is not bound to whatever medium upon which it is encoded.
Example: The information in a book can be copied onto any other medium without the information changing in any way and without relocation of the material medium upon which it is encoded:
Reading a book: If information and minds were both physical, it would be impossible to receive (read) the information in a book without relocating the material of the book into the brain of the reader.
Reading a printed message to another person: If information and minds were both physical, it would be impossible to convey (read aloud) the information in a book without relocating the material of the book into the brain of the listener.
Speaking to an audience: If information and minds were both physical, it would be impossible to share information with an audience without relocating the material of the provider's brain to the brains of the each member of the audience.
10 Laws of Nature Regarding Information which verify that creation is true and evolution is false:
The following is a transcript of Dr. Werner Gitt from his book, "In the Beginning Was Information".
Premises:
Anything material, such as physical/chemical processes, cannot create something non-material
Information is a non-material fundamental entity and not a property of matter
Information requires a material medium for storage and transmission
Information cannot arise from statistical processes
There can be no information without a code - no thought or idea can be shared without a code
All codes result from an intentional choice and agreement between sender and recipient
The determination of meaning for and from a set of symbols is a mental process that requires intelligence
There can be no new information without an intelligent, purposeful sender
Any given chain of information can be traced back to an intelligent source
Information comprises the non-material foundation for all:
technological systems
works of art
biological systems
Therefore,
Since the DNA code of all life is clearly within the definition domain of information, we conclude that there must be a sender
Since the density and complexity of the DNA encoded information is billions of times greater than man's present technology, we conclude that the sender must be supremely intelligent
Since the sender must have
encoded (stored) the information into the DNA molecules,
constructed the molecular biomachines required for the encoding, decoding, and synthesizing process and,
designed all the features for the original life forms,
We conclude the sender must be purposeful and supremely powerful,
Since information is a non-material fundamental entity and cannot originate from material quantities, we conclude that the sender must have a non-material component
Since information is a non-material fundamental entity and cannot originate from material quantities, and since information also originates from man, we conclude man's nature must have a non-material component (spirit)
Since information is a non-material entity, we conclude that the assumption "the universe is comprised solely of mass and energy" is false.
Since:
biological information originates only from an intelligent sender and,
all theories of chemical and biological evolution require that information must originate solely from mass and energy alone (without a sender), we conclude that all theories or concepts of biological evolution are false.
Anyone who disagrees with these laws and conclusions must falsify them by demonstrating the initial origin of information from purely material sources. Therefore, the laws of nature about information have,
refuted the assumption of scientific materialism and the theories of chemical and biological evolution
all philosophies or theories based on the assumption of scientific materialism including chemical and biological evolution are falsified by the laws of nature about information.
Shannon Information
Shannon Information is not the type of information that DNA possesses, and does not require intelligence to be produced. Unlike Shannon Information, genetic information is complex, specified, prescriptive, functional, meaningful, purposeful, semiotic, and linguistic.
Information scientist Dr. Werner Gitt on Shannon Information:
"Shannon's definition of information exclusively concerns the statistical properties of sequences of symbols; meaning is completely ignored. It follows that this concept of information is unsuitable for evaluating the information content of meaningful sequences of symbols. A message which has been subject to interference or "noise", in general comprises more information than an error-free message, according to Shannon's theory. It follows that this concept of information is unsuitable for evaluating the information content of meaningful sequences of symbols."
- In the Beginning Was Information, Werner Gitt, former head of the Department of Information Technology at the German Federal Institute of Physics and Technology (Physikalisch-Technische Bundesanstalt [PTB], in Braunschweig). Seven years later he was promoted to Director and Professor at PTB.
Sources
"The information in DNA is stored as a code made up of four chemical bases: adenine (A), guanine (G), cytosine (C), and thymine (T). Human DNA consists of about 3 billion bases, and more than 99 percent of those bases are the same in all people. The order, or sequence, of these bases determines the information available for building and maintaining an organism, similar to the way in which letters of the alphabet appear in a certain order to form words and sentences." - What is DNA?, Genetics Home Reference, NLH, U.S. National Library of Medicine
"It should now be clear that information, being a fundamental entity, cannot be a property of matter, and its origin cannot be explained in terms of material processes. We therefore formulate the following fundamental theorem: Theorem 1: The fundamental quantity information is a nonmaterial (mental) entity. It is not a property of matter, so that purely material processes are fundamentally precluded as sources of information." - Werner Gitt, In the Beginning was Information. 2000, former Director, former head of the Department of Information Technology at the German Federal Institute of Physics and Technology (Physikalisch-Technische Bundesanstalt [PTB], in Braunschweig
"If there are more than several dozen nucleotides in a functional sequence, we know that realistically they will never just "fall into place"'. This has been mathematically demonstrated repeatedly. But as we will soon see, neither can such a sequence arise randomly one nucleotide at a time. A pre-existing "concept" is required as a framework upon which a sentence or a functional sequence must be built. Such a concept can only pre-exist within the mind of the author." - Genetic Entropy & the Mystery of the Genome, Dr, Johnathon Sanford, geneticist, Cornell University, 2005, pp. 124-125.
"No matter how many "bits" of possible combinations it has, there is no reason to call it "information" if it doesn't at least have the potential of producing something useful. What kind of information produces function? In computer science, we call it a "program." Another name for computer software is an "algorithm." No man-made program comes close to the technical brilliance of even Mycoplasmal genetic algorithms. Mycoplasmas are the simplest known organisms with the smallest known genome, to date. How was its genome and other living organisms' genomes programmed?" - , David L. Abel1 and Jack T. Trevors" Three subsets of sequence complexity and their relevance to biopolymeric information, David L. Abel and Jack T. Trevors, 2005
"The Common Fund's 4D Nucleome program aims to understand the principles behind the three-dimensional organization of the nucleus in space and time (the 4th dimension), the role nuclear organization plays in gene expression and cellular function, and how changes in the nuclear organization affect normal development as well as various diseases." - The 4D Nucleome Project, National Institutes of Health, https://commonfund.nih.gov/4Dnucleome
"There are no specific choices to be found anywhere within this mathematical definition of a "bit." Shannon worked only on general communication engineering problems. He deliberately made no attempt to quantify intuitive/semantic information by measuring specific functional choices with fixed units. That would be impossible." - Dichotomy in the definition of prescriptiveinformation suggests both prescribed data and prescribed algorithms: biosemiotics applications in genomic systems, David J D'Onofrio, David L Abel and Donald E Johnson, Theoretical Biology and Medical Modeling, 2012
The human genome takes shape and shifts over time, Sarah Schwartz, August 24, 2015 https://www.sciencenews.org/article/human-genome-takes-shape-and-shifts-over-time
"The digital linear coding carried by the base pairs in the DNA double helix is now known to have an important component that acts by altering, along its length, the natural shape and stiffness of the molecule. In this way, one region of DNA is structurally distinguished from another, constituting an additional form of encoded information manifest in three-dimensional space. These shape and stiffness variations help in guiding and facilitating the DNA during its three-dimensional spatial interactions. Such interactions with itself allow communication between genes and enhanced wrapping and histone-octamer binding within the nucleosome core particle. Meanwhile, interactions with proteins can have a reduced entropic binding penalty owing to advantageous sequence-dependent bending anisotropy. Sequence periodicity within the DNA, giving a corresponding structural periodicity of shape and stiffness, also influences the supercoiling of the molecule, which, in turn, plays an important facilitating role. In effect, the super-helical density acts as an analogue regulatory mode in contrast to the more commonly acknowledged purely digital mode."
http://rsta.royalsocietypublishing.org/content/370/1969/2960
"The creation of information is habitually associated with concious activity" - Henry Quastier, information theorist
Information is useless unless it can be read. But the decoding machinery is itself encoded on the DNA. The leading philosopher of science, Karl Popper (1902-1994), expressed the huge problem:
"What makes the origin of life and of the genetic code a disturbing riddle is this: the genetic code is without any biological function unless it is translated; that is, unless it leads to the synthesis of the proteins whose structure is laid down by the code. But . . . the machinery by which the cell (at least the non-primitive cell, which is the only one we know) translates the code consists of at least fifty macromolecular components which are themselves coded in the DNA. Thus the code can not be translated except by using certain products of its translation. This constitutes a baffling circle; a really vicious circle, it seems, for any attempt to form a model or theory of the genesis of the genetic code. Thus we may be faced with the possibility that the origin of life (like the origin of physics) becomes an impenetrable barrier to science, and a residue to all attempts to reduce biology to chemistry and physics." - 1974. Scientific Reduction and the Essential Incompleteness of All Science. In Ayala, F. and Dobzhansky, T., eds., Studies in the Philosophy of Biology, University of California Press, Berkeley, p. 270
"Did the code and the means of translating it appear simultaneously in evolution? It seems almost incredible that any such coincidences could have occurred, given the extraordinary complexities of both sides and the requirement that they be coordinated accurately for survival. By a pre-Darwinian (or a skeptic of evolution after Darwin) this puzzle surely would have been interpreted as the most powerful sort of evidence for special creation." - C. Haskins, "Advances and Challenges in Science" in American Scientist 59 (1971), pp. 298.
"The information content of amino acid sequences cannot increase until a genetic code with an adapter function has appeared. Nothing which even vaguely resembles a code exists in the physiochemical world. One must conclude that no valid scientific explanation of the origin of life exists at present." - H. Yockey, "Self Organization Origin of Life Scenarios and Information Theory," in Journal of Theoretical Biology 91 (1981), p. 13.
"On the possibility that random material causes could be the origin of proteins: If we have a tiny chain of only 10 amino acid molecules, and because there are 20 amino acid molecules that can be used to produce the chain, there are 10 trillion possible combinations! The probability that a sequence of amino acids could arise to produce even such a tiny protein are astronomical, and therefore beyond improbable. By the science of statistical analysis, this would be considered impossible times impossible times impossible. . . An average protein however, is 300-500 amino acid molecules in length and may be thousands, and results in trillons times trillions of potential combinations! Here we see that the improbability of material causes to arrange a sequence for a typical protein is far beyond improbable, so as to be unworthy of being considered possible by any manner of reasoning." - Stephen C. Meyer, PhD in Philosophy of Science and Mathematics, former geophysicist for Atlantic Richfield Company (ARCO). His PhD thesis offered a methodological interpretation of origin-of-life research. Meyer discovered that the odds of a protein forming naturally is 1:10^164 There are only 10^80 elementary particles in the known universe. There are only 10^18 seconds in the imagined 13.5 billions years since the big bang.
"Representation and processing of digital information in the form of DNA is essential to life in all organisms, no matter how large or tiny. Computing tools and computational thinking help us understand how DNA stores information and how that information directs activity in the cell." - Module 6: Digital DNA, University of British Columbia http://www.cs.ubc.ca/~condon/cpsc101/notes/digital-dna.pdf
"Genomes [all the DNA of a species] are remarkable in that they encode most of the functions necessary for their interpretation and propagation." - Anne-Claude Gavin et al., "Proteome Survey Reveals Modularity of the Yeast Cell Machinery," Nature, Vol. 440, 30 March 2006, p. 631.
"The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of DNA structure account for much of its remarkable impact on science: it's digital nature and its complementarity, whereby one strand of the helix binds perfectly with its partner. DNA has two types of digital information -- the genes that encode proteins, which are the molecular machines of life, and the gene regulatory networks that specify the behavior of the genes." - Hood L1, Galas D. The digital code of DNA, http://www.ncbi.nlm.nih.gov/pubmed/12540920
"Biologic systems and processes cannot be fully accounted for in terms of the principles and laws of physics and chemistry alone, but they require in addition the principles of semiotics - the science of symbols and signs, including linguistics." - Rutgers University professor Sungchul Ji's, "The Linguistics of DNA: Words, Sentences, Grammar, Phonetics, and Semantics"
The Information Theory textbook, "T. M. Cover and J. M. Thomas, Elements of Information Theory, 2nd, Wiley-Interscience, 2006." states information is knowledge transmitted from sender to receiver using a code.
"We now know that genes are made of DNA, a magnificently simple/complex molecule which actually encodes a language. It carries information just as a book does. The language has 4 letters which form 64 three letter words." The digital code of DNA http://www.ncbi.nlm.nih.gov/pubmed/12540920
"There is no such thing as physical information. Information is a nonmaterial fundamental entity and not a property of matter. Information is knowledge conveyed from a sender to a receiver using a language agreed upon by both parties. Nature has no potential to create information, and therefore cannot be the origin of living things. Information is a non-physical fundamental entity, which the laws of physics and matter cannot produce. Information is a product of a non-physical mind. No physical thing is itself information. Observing something allows us to gain knowledge of it's properties, which we can convey to someone else, thus producing information by sharing the knowledge we have gained by observation, investigation, or study." - Werner Gitt, former Director, former head of the Department of Information Technology at the German Federal Institute of Physics and Technology (Physikalisch-Technische Bundesanstalt [PTB], in Braunschweig
"Information is information, not matter or energy." - Norbert Wiener, Cybernetics; or, Control and Communication in the Animal and the Machine, 2nd edition (Cambridge, Massachusetts: MIT Press, 1948), p. 132.
"There is no known law of nature, no known process and no known sequence of events which can cause information to originate by itself in matter." - Werner Gitt, former Director, former head of the Department of Information Technology at the German Federal Institute of Physics and Technology (Physikalisch-Technische Bundesanstalt [PTB], in Braunschweig
"In all systems, there can be no new information without an intelligent, purposeful sender." - Werner Gitt, former Director, former head of the Department of Information Technology at the German Federal Institute of Physics and Technology (Physikalisch-Technische Bundesanstalt [PTB], in Braunschweig
"No matter how many "bits" of possible combinations it has, there is no reason to call it "nformation" if it doesn't at least have the potential of producing something useful. What kind of information produces function? In computer science, we call it a "program." Another name for computer software is an 'algorithm.' No man-made program comes close to the technical brilliance of even Mycoplasmal genetic algorithms. Mycoplasmas are the simplest known organisms with the smallest known genome, to date. How was its genome and other living organisms' genomes programmed?" Abel and Trevors, p. 8.
How can we measure information? A computer file might contain information for printing a story, reproducing a picture at a given resolution, or producing a widget to specified tolerances. Information can usually be compressed to some degree, just as the English language could be compressed by eliminating every "u" that directly follows a "q". If compression could be accomplished to the maximum extent possible (eliminating all redundancies and unnecessary information), the number of bits (0s or 1s) would be a measure of the information needed to produce the story, picture, or widget.
Each living system can be described by its age and the information stored in its DNA. Each basic unit of DNA, called a nucleotide, can be one of four types. Therefore, each nucleotide represents two (log24 = 2) bits of information. Conceptual systems, such as ideas, a filing system, or a system for betting on race horses, can be explained in books. Several bits of information can define each symbol in these books. The number of bits of information, after compression, needed to duplicate and achieve the purpose of a system will be defined as its information content. That number is also a measure of the system's complexity.
"No matter how many 'bits' of possible combinations it has, there is no reason to call it 'information' if it doesn't at least have the potential of producing something useful. What kind of information produces function? In computer science, we call it a 'program.' Another name for computer software is an 'algorithm.' No man-made program comes close to the technical brilliance of even Mycoplasmal genetic algorithms. Mycoplasmas are the simplest known organisms with the smallest known genome, to date. How was its genome and other living organisms' genomes programmed?" Abel and Trevors, p. 8.
"If there are more than several dozen nucleotides in a functional sequence, we know that realistically they will never just 'fall into place.' This has been mathematically demonstrated repeatedly. But as we will soon see, neither can such a sequence arise randomly one nucleotide at a time. A pre-existing 'concept' is required as a framework upon which a sentence or a functional sequence must be built. Such a concept can only pre-exist within the mind of the author." Sanford, pp. 124-125.
"The creation of information is habitually associated with conscious activity" - Henry Quastier, information theorist
On the possibility that random material causes could be the origin of proteins: If we have a tiny chain of only 10 amino acid molecues, and because there are 20 amino acid molecules that can be used to produce the chain, there are 10 trillion possible combinations! The probability that a sequence of amino acids could arise to produce even such a tiny protein are astronomical, and therefore beyond improbable. By the science of statistical analysis, this would be considered impossible times impossible times impossible. . . An average protein however, is 300-500 amino acid molecules in length and may be thousands, and results in trillons times trillions of potential combinations! Here we see that the improbability of material causes to arrange a sequence for a typical protein is far beyond improbable, so as to be unworthy of being considered possible by any manner of reasoning.
Stephen C. Meyer earned a PhD in Philosophy of Science and also Mathematics, former geophysicist for Atlantic Richfield Company (ARCO). His PhD thesis offered a methodological interpretation of origin-of-life research. Meyer discovered that the odds of a protein forming naturally is 1:10^164 There are only 10^80 elementary particles in the known universe. There are only 10^18 seconds in the imagined 13.5 billions years since the big bang.
Michael Polanyi (1891-1976), former chairman of physical chemistry at the University of Manchester (UK) who turned to philosophy, affirmed a very important point -- the information was something above the chemical properties of the building blocks:
"As the arrangement of a printed page is extraneous to the chemistry of the printed page, so is the base sequence in a DNA molecule extraneous to the chemical forces at work in the DNA molecule. It is this physical indeterminacy of the sequence that produces the improbability of any particular sequence and thereby enables it to have a meaning - a meaning that has a mathematically determinate information content."
University of British Columbia - Module 6: Digital DNA: "Representation and processing of digital information in the form of DNA is essential to life in all organisms, no matter how large or tiny. Computing tools and computational thinking help us understand how DNA stores information and how that information directs activity in the cell." http://www.cs.ubc.ca/~condon/cpsc101/notes/digital-dna.pdf
In 2010, another level of complexity was discovered in the genetic code. On a strand of DNA, a sequence of three adjacent nucleotides forms a unit in the genetic code called a codon. Prior to 2010, some codons were thought to have the same function as others. That turns out to not be the case:
"... synonymous codon changes can so profoundly change the role of a protein [that it] adds a new level of complexity to how we interpret the genetic code. Ivana Weygand-Durasevic and Michael Ibba, "New Roles for Codon Usage," Science, Vol. 329, 17 September 2010, p. 1474. Also see Fangliang Zhang et al., Differential Arginylation of Actin Isoforms Is Regulated by Coding Sequence-Dependent Degradation, Science, Vol. 329, 17 September 2010, p. 1734-1537.
"Genomes [all the DNA of a species] are remarkable in that they encode most of the functions necessary for their interpretation and propagation." Anne-Claude Gavin et al., "Proteome Survey Reveals Modularity of the Yeast Cell Machinery," Nature, Vol. 440, 30 March 2006, p. 631.
TRANSLATION PACKAGE NEEDED AT BEGINNING - The amount of information in the genetic code is so vast that it would be impossible to put together by chance. But, in addition, there must be a means of translating it so the tissues can use the code. "Did the code and the means of translating it appear simultaneously in evolution? It seems almost incredible that any such coincidences could have occurred, given the extraordinary complexities of both sides and the requirement that they be coordinated accurately for survival. By a pre-Darwinian (or a skeptic of evolution after Darwin) this puzzle surely would have been interpreted as the most powerful sort of evidence for special creation." - C. Haskins, "Advances and Challenges in Science" in American Scientist 59 (1971), pp. 298.
"Not only did the DNA have to originate itself by random accident, but the translation machinery already had to be produced by accident - and also immediately! Without it, the information in the DNA could not be applied to the tissues. Instant death would be the result. "The code is meaningless unless translated. The modern cell's translation machinery consists of at least fifty macromolecular components which are themselves encoded in DNA [!]; the code cannot be translated otherwise than by products of translation. It is the modern expression of omne vivum ex ovo ['every living thing comes from an egg']. When and how did this circle become closed? It is exceedingly difficult to imagine." - J, Monod, Chance and Necessity (1971), p. 143.
"The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of DNA structure account for much of its remarkable impact on science: it's digital nature and its complementarity, whereby one strand of the helix binds perfectly with its partner. DNA has two types of digital information--the genes that encode proteins, which are the molecular machines of life, and the gene regulatory networks that specify the behaviour of the genes." http://www.ncbi.nlm.nih.gov/pubmed/12540920
Shannon was keen to point out that the type of information he described did not relate to function. It was a reductionist approach to reducing improbability, and that the more possibilities of an event, the more information it could provide. An example might be the rolling of a die. Since the die has 5 sides, it provides 6 possible outcomes, and therefore 6 seperate pieces of information. When the die is rolled, the outcome has been reduced from 6 to 1, and the information has been reduced to 1 piece of information. However, genetic information is not based upon chance, necessity as it relates to chemistry, or statistical analysis. In fact, statistical analysis itself cannot produce information, but rather is a process of studying information. Genetic information is complex and specific, and relates to function. Shannon information does not describe genetic information. Complex specified information is a critical component of life and is not statistical or produced by chance events. Complex specified information is a product of mind and not random associations or events. Protein synthesis, gene expression, the precise structure of proteins which determines function, and meta-information of the cell are therefore not products of chance or random associations, but instead a feature of intentional design.
Receiver (information theory): The receiver in information theory is the receiving end of a communication channel. It receives decoded messages/information from the sender, who first encoded them. Sometimes the receiver is modeled so as to include the decoder. Real-world receivers like radio receivers or telephones can not be expected to receive as much information as predicted by the noisy channel coding theorem. https://en.wikipedia.org/wiki/Receiver_(information_theory)
Information: Information is that which informs. In other words, it is the answer to a question of some kind. It is thus related to data and knowledge, as data represents values attributed to parameters, and knowledge signifies understanding of real things or abstract concepts.[1] As it regards data, the information's existence is not necessarily coupled to an observer (it exists beyond an event horizon, for example), while in the case of knowledge, the information requires a cognitive observer. Information is conveyed either as the content of a message or through direct or indirect observation of anything. That which is perceived can be construed as a message in its own right, and in that sense, information is always conveyed as the content of a message. Information can be encoded into various forms for transmission and interpretation (for example, information may be encoded into a sequence of signs, or transmitted via a sequence of signals). It can also be encrypted for safe storage and communication. https://en.wikipedia.org/wiki/Information
DNA, RNA, and the Flow of Genetic Information http://www.ncbi.nlm.nih.gov/books/NBK21171/
Genetics - information properties https://ghr.nlm.nih.gov/primer/basics/dna
"Biologic systems and processes cannot be fully accounted for in terms of the principles and laws of physics and chemistry alone, but they require in addition the principles of semiotics - the science of symbols and signs, including linguistics." - Rutgers University professor Sungchul Ji's, "The Linguistics of DNA: Words, Sentences, Grammar, Phonetics, and Semantics"
The Information Theory (textbook), "T. M. Cover and J. M. Thomas, Elements of Information Theory, 2nd, Wiley-Interscience, 2006." states information is knowledge transmitted from sender to receiver using a code.
"We now know that genes are made of DNA, a magnificently simple/complex molecule which actually encodes a language. It carries information just as a book does. The language has 4 letters which form 64 three letter words." The digital code of DNA http://www.ncbi.nlm.nih.gov/pubmed/12540920
Websters Dictionary, Definition of algorithm: a procedure for solving a mathematical problem (as of finding the greatest common divisor) in a finite number of steps that frequently involves repetition of an operation; broadly :a step-by-step procedure for solving a problem or accomplishing some end especially by a computer
DNA is information organized to conform to linguistics laws which are more complex than Zipf's Law of Linguistics, it is digital code, is posesses algorithmic operations, and the human language properties of semantics, puntiuation, grammar, phonetics, and aprobatics.
INFORM: to communicate knowledge, to inform Definition of -ation: action or process flirtation : something connected with an action or process discoloration INFORM -ATION = INFORMATION
Websters Definition of knowledge 1 a (1): the fact or condition of knowing something with familiarity gained through experience or association (2): acquaintance with or understanding of a science, art, or techniqueb (1) : the fact or condition of being aware of something (2): the range of one's information or understanding answered to the best of my knowledgec: the circumstance or condition of apprehending truth or fact through reasoning: cognitiond: the fact or condition of having information or of being learned a person of unusual knowledge 2 a: the sum of what is known: the body of truth, information, and principles acquired by humankindb archaic: a branch of learning
The Heavy Hammer of Information http://nephilimfree.blogspot.com/
"Information is information, not matter or energy." - Norbert Wiener, Cybernetics; or, Control and Communication in the Animal and the Machine, 2nd edition (Cambridge, Massachusetts: MIT Press, 1948), p. 132.
"There is no known law of nature, no known process and no known sequence of events which can cause information to originate by itself in matter." - Werner Gitt, former Director, former head of the Department of Information Technology at the German Federal Institute of Physics and Technology (Physikalisch-Technische Bundesanstalt [PTB], in Braunschweig
"In all systems, there can be no new information without an intelligent, purposeful sender." - Werner Gitt, former Director, former head of the Department of Information Technology at the German Federal Institute of Physics and Technology (Physikalisch-Technische Bundesanstalt [PTB], in Braunschweig
Proceedings of the Symposium, Cornell University, USA, 31 May - 3 June 2011 http://www.worldscientific.com/worldscibooks/10.1142/8818#t=toc"
"In the spring of 2011, a diverse group of scientists gathered at Cornell University to discuss their research into the nature and origin of biological information. This symposium brought together experts in information theory, computer science, numerical simulation, thermodynamics, evolutionary theory, whole organism biology, developmental biology, molecular biology, genetics, physics, biophysics, mathematics, and linguistics. This volume presents new research by those invited to speak at the conference.
The contributors to this volume use their wide-ranging expertise in the area of biological information to bring fresh insights into the many explanatory difficulties associated with biological information. These authors raise major challenges to the conventional scientific wisdom, which attempts to explain all biological information exclusively in terms of the standard mutation/selection paradigm.
Several clear themes emerged from these research papers: 1) Information is indispensable to our understanding of what life is; 2) Biological information is more than the material structures that embody it; 3) Conventional chemical and evolutionary mechanisms seem insufficient to fully explain the labyrinth of information that is life. By exploring new perspectives on biological information, this volume seeks to expand, encourage, and enrich research into the nature and origin of biological information."
In the Beginning was Information - Werner Gitt, former Director, former head of the Department of Information Technology at the German Federal Institute of Physics and Technology (Physikalisch-Technische Bundesanstalt [PTB], in Braunschweig
DNA Study Forces Rethink of What It Means to Be a Gene, Eliizabeth Pennisi, Science 15 June 2007, Vol. 316 no. 5831 pp. 1556-1557: "According to a painstaking new analysis of 1% of the human genome, genes can be sprawling, with far-flung protein-coding and regulatory regions that overlap with other genes." http://www.sciencemag.org/content/316/5831/1556
Anzai, T. et al. 2003. Comparative sequencing of human and chimpanzee MHC class I regions unveils insertions/deletions as the major path to genomic divergence. Proceedings of the National Academy of Sciences. 100 (13): 7708-13.
Yale News: Yale Symposium Will Explore New Evidence Supporting The Theory of Intelligent Design http://news.yale.edu/2000/10/31/yale-symposium-will-explore-new-evidence-supporting-theory-intelligent-design
SYMPOSIUM PRELIMINARY PROGRAM Intelligent Design & Artificial Intelligence: The Ghost in the Machine http://sophiawarsaw.ippt.gov.pl/Symposium%202009%20Pasadena.pdf
The 2016 International Conference on Biological Information and Biomedical Engineering http://www.icbibe.org/
"Many biologists think of the developmental processes by which organisms progress from egg to adult in terms of the execution of a "developmental program" - Biological Information, Stanford Encyclopedia of Philosophy
"Since the 1950s, the concept of information has acquired a strikingly prominent role in many parts of biology." - Stanford Encyclopedia of Philosophy https://plato.stanford.edu/entries/information-biological/
Biological Information, New Perspectives, Proceedings of the Symposium, Cornell University, USA, 31 May - 3 June 2011
John W. Oller, Jr (2013) Pragmatic Information. Biological Information: pp. 64-86. doi: .1142/9789814508728_0003
Section one: Information Theory & Biology: Introductory Comments, Pragmatic Information, John W. Oller, Jr, Doris B. Hawthorne Board of Regents Support Fund Professor IV, Department of Communicative Disorders, University of Louisiana at Lafayette, Lafayette, LA 70504, USA
The goal of this paper is to define pragmatic information with a view toward measuring it. Here, pragmatic information means the content of valid signs - the key that unlocks language acquisition by babies and to human communication through language - also the content that enables biological "codes" in genetics, embryology, and immunology to work. In such systems, the inter-related layers appear to be ranked as in a hierarchy. Sounds are outranked by syllables, in turn outranked by words, and so on. In DNA, nucleotide pairs are outranked by codons, which are outranked by genes, and so on. As signs of lower rank combine to form signs of any higher rank, combinatorial "explosions" occur. With each increase in rank, the number of possible combinations grows exponentially, but the constraints on valid strings and, thus, their pragmatic value, sharpens their focus. As a result with each explosive increase in the number of possible combinations the relative proportion of meaningful ones diminishes. Consequently, random processes of forming strings or changing them must tend increasingly toward meaninglessness (invalid and nonviable) strings. The consequent outcome of random mutations is mortality of individuals and in deep time an increasing number of disorders, diseases, and the eventual extinction of populations.
Computational Aspects of Biological Information 2016 https://www.microsoft.com/en-us/research/event/computational-aspects-biological-information-2016/#
9th International Conference on Bioinformatics, November 13-14, 2017 Paris, France http://bioinformatics.conferenceseries.com/
Signal Transduction in the Immune System http://www.faseb.org/src/micro/Site/SigImm/home.aspx
Biochemistry. 5th edition: Chapter 5DNA, RNA, and the Flow of Genetic Information http://www.ncbi.nlm.nih.gov/books/NBK21171/
Biological Information, New Perspectives, Proceedings of the Symposium, Cornell University, USA, 31 May - 3 June 2011 Edited by: Robert J Marks II (Baylor University, USA), Michael J Behe (Lehigh University, USA), William A Dembski (Discovery Institute, USA), Bruce L Gordon (Houston Baptist University, USA), John C Sanford (Cornell)
Biological Information, New Perspectives http://www.worldscientific.com/worldscibooks/10.1142/8818#t=toc%22n the spring of 2011, a diverse group of scientists gathered at Cornell University to discuss their research into the nature and origin of biological information. This symposium brought together experts in information theory, computer science, numerical simulation, thermodynamics, evolutionary theory, whole organism biology, developmental biology, molecular biology, genetics, physics, biophysics, mathematics, and linguistics. This volume presents new research by those invited to speak at the conference.
The contributors to this volume use their wide-ranging expertise in the area of biological information to bring fresh insights into the many explanatory difficulties associated with biological information. These authors raise major challenges to the conventional scientific wisdom, which attempts to explain all biological information exclusively in terms of the standard mutation/selection paradigm.
Several clear themes emerged from these research papers: 1) Information is indispensable to our understanding of what life is; 2) Biological information is more than the material structures that embody it; 3) Conventional chemical and evolutionary mechanisms seem insufficient to fully explain the labyrinth of information that is life. By exploring new perspectives on biological information, this volume seeks to expand, encourage, and enrich research into the nature and origin of biological information.
Session One - Information Theory & Biology: Introductory Comments (Robert J Marks II): Biological Information - What is It? (Werner Gitt, Robert Compton and Jorge Fernandez), A General Theory of Information Cost Incurred by Successful Search (William A Dembski, Winston Ewert and Robert J Marks II), Pragmatic Information (John W Oller, Jr), Limits of Chaos and Progress in Evolutionary Dynamics (William F Basener), Tierra: The Character of Adaptation (Winston Ewert, William A Dembski and Robert J Marks II), Multiple Overlapping Genetic Codes Profoundly Reduce the Probability of Beneficial Mutation (George Montanez, Robert J Marks II, Jorge Fernandez and John C Sanford), Entropy, Evolution and Open Systems (Granville Sewell), Information and Thermodynamics in Living Systems (Andy C McIntosh)
Session Two - Biological Information and Genetic Theory: Introductory Comments (John C Sanford): Not Junk After All: Non-Protein-Coding DNA Carries Extensive Biological Information (Jonathan Wells) Can Purifying Natural Selection Preserve Biological Information? (Paul Gibson, John R Baumgardner, Wesley H Brewer and John C Sanford), Selection Threshold Severely Constrains Capture of Beneficial Mutations (John C Sanford, John R Baumgardner and Wesley H Brewer)
Using Numerical Simulation to Test the "Mutation-Count" Hypothesis (Wesley H Brewer, John R Baumgardner and John C Sanford), Can Synergistic Epistasis Halt Mutation Accumulation? Results from Numerical Simulation (John R Baumgardner, Wesley H Brewer and John C Sanford), Computational Evolution Experiments Reveal a Net Loss of Genetic Information Despite Selection (Chase W Nelson and John C Sanford), Information Loss: Potential for Accelerating Natural Genetic Attenuation of RNA Viruses (Wesley H Brewer, Franzine D Smith and John C Sanford), DNA.EXE: A Sequence Comparison between the Human Genome and Computer Code (Josiah Seaman), Biocybernetics and Biosemiosis (Donald Johnson)
Session Three - Theoretical Molecular Biology: Introductory Comments (Michael J Behe): An Ode to the Code: Evidence for Fine-Tuning in the Standard Codon Table (Jed C Macosko and Amanda M Smelser), A New Model of Intracellular Communication Based on Coherent, High-Frequency Vibrations in Biomolecules (L Dent), Getting There First: An Evolutionary Rate Advantage for Adaptive Loss-of-Function Mutations (Michael J Behe), The Membrane Code: A Carrier of Essential Biological Information That is Not Specified by DNA and is Inherited Apart from It (Jonathan Wells), Explaining Metabolic Innovation: Neo-Darwinism Versus Design (Douglas D Axe and Ann K Gauger)
Session Four - Biological Information and Self-Organizational Complexity Theory: Introductory Comments (Bruce L Gordon): Evolution Beyond Entailing Law: The Roles of Embodied Information and Self Organization (Stuart Kauffman), Towards a General Biology: Emergence of Life and Information from the Perspective of Complex Systems Dynamics (Bruce H Weber)
Werner Gitt (Professor of Information Systems) describes man as the most complex information processing system on earth. Gitt estimated that about 3 x 1024 bits of information are processed daily in an average human body. That is thousands of times more than all the information in all the world's libraries. [See Werner Gitt, In the Beginning Was Information, 2nd edition (Bielefeld, Germany: CLV, 2000), p. 88.]
The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of DNA structure account for much of its remarkable impact on science: its digital nature and its complementarity, whereby one strand of the helix binds perfectly with its partner. DNA has two types of digital information--the genes that encode proteins, which are the molecular machines of life, and the gene regulatory networks that specify the behaviour of the genes.
http://www.ncbi.nlm.nih.gov/pubmed/12540920
"The basic flaw of all evolutionary views is the origin of the information in living beings. It has never been shown that a coding system and semantic information could originate by itself in a material medium, and the information theorems predict that this will never be possible. A purely material origin of life is thus precluded." - Werner Gitt, former Director, former head of the Department of Information Technology at the German Federal Institute of Physics and Technology (Physikalisch-Technische Bundesanstalt [PTB], in Braunschweig
Three prerequisites must be fulfilled in order for the German Ministerium to award the title "Director and Professor" at a German research institute, on the recommendation of the Praesidium. The person concerned must be: 1. A scientist (i.e., it is most definitely an academic title). 2. One who has published a significant number of original research papers in the technical literature. 3 .Must head a department in his area of expertise, in which several working scientists are employed.
"It was already clear that the genetic code is not merely an abstraction, but also the embodiment of life's mechanisms; the consecutive triplets of nucleotides in DNA (called codons) are inherited but they also guide the construction of proteins. So it is disappointing, but not surprising, that the origin of the genetic code is still as obscure as the origin of life itself." - John Maddox, "The Genetic Code by Numbers," Nature, Vol. 367, 13 January 1994, p. 111.
"We estimate that approximately 73% of all protein-coding SNVs and approximately 86% of SNVs predicted to be deleterious arose in the past 5,000-10,000?years." - Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants http://www.nature.com/nature/journal/v493/n7431/full/nature11690.html
The Linguistics of DNA Words, Sentences, Grammar, Phonetics and Semantics http://www.genetics.org/search?fulltext=information&submit=yes&x=0&y=0
Quantitative linguistic study of DNA sequences "A new family of compound Poisson distribution functions from quantitative linguistics is used to study the linguistic features of DNA sequences that go beyond the Zipf's law." http://www.sciencedirect.com/science/article/pii/S0378437102017879
Linguistics Features of Noncoding DNA Sequences http://cps.bu.edu/hes/articles/mbghpss94.pdf Complexity Matters "Evolutionary biologists have been loosely divided into two camps. One group believes that all characteristics of an organism are equally malleable by evolutionary pressures, with the result that an organism can in theory take any shape. The other camp has the view that there are fundamental properties of each organism that are quite immutable. In his commentary, Wagner discusses new work on the complexity of organisms and a paper by Waxman and Peck in this week's issue and argues that these results tip the balance in favor of the group that believes in a fundamentally immutable set of characteristics for each organism." http://www.sciencemag.org/content/279/5354/1158.summary
Scientists discover double meaning in genetic code: "Scientists have discovered a second code hiding within DNA. The second code contains information that changes how scientists read the instructions contained in DNA and interpret mutations to make sense of health and disease. Genomes use the genetic code to write two separate languages. One describes how proteins are made, and the other instructs the cell on how genes are controlled. One language is written on top of the other." http://www.sciencedaily.com/releases/2013/12/131212142151.htm
Module 6: Digital DNA http://www.cs.ubc.ca/~condon/cpsc101/notes/digital-dna.pdf
The digital code of DNA. http://www.ncbi.nlm.nih.gov/pubmed/12540920
"Information theory tells us that the only known way to decrease the entropy of an isolated system is by having intelligence in that system. [See, for example, Charles H. Bennett, "Demons, Engines and the Second Law," - Scientific American, Vol. 257, November 1987, pp. 108-116.] Because the universe is far from its maximum entropy level, a vast intelligence is the only known means by which the universe could have been brought into being. [See also "Second Law of Thermodynamics" on page 31.]
"Any living being possesses an enormous amount of "intelligence," very much more than is necessary to build the most magnificent of cathedrals. Today, this "intelligence" is called "information," but it is still the same thing. It is not programmed as in a computer, but rather it is condensed on a molecular scale in the chromosomal DNA or in that of any other organelle in each cell. This "intelligence" is the sine qua non of life. If absent, no living being is imaginable. Where does it come from? This is a problem which concerns both biologists and philosophers and, at present, science seems incapable of solving it." - Pierre P. Grasse, The Evolution of Living Organisms, 1977, p. 168
"Information is a non-physical fundamental entity, which the laws of physics and matter cannot produce. Information is a product of a non-physical mind. No physical thing is itself information. Observing something allows us to gain knowledge of it's properties, which we can convey to someone else, thus producing information by sharing the knowledge we have gained by observation, investigation, or study." - Gitt Werner, former head of the Department of Information Technology at the German Federal Institute of Physics and Technology (Physikalisch-Technische Bundesanstalt [PTB], in Braunschweig https://www.ptb.de/cms/en.html). Seven years later he was promoted to Director and Professor at PTB. https://www.youtube.com/watch?v=DA0Ojxr4pv0
"Information is information, neither matter nor energy. Any materialism which disregards this, will not survive one day." - Norbert Wiener, Mathematician, Cybernetics; or, Control and Communication in the Animal and the Machine, 2nd edition (Cambridge, Massachusetts: MIT Press, 1948), p. 132.
"Even the biology based on a materialistic philosophy, which discarded all vitalistic and metaphysical components, did not readily accept the reduction of biology to physics ... Information is neither a physical nor a chemical principle like energy and matter, even though the latter are required as carriers." - East German scientist J. Peil