Molecules don't care if they are assembled in a way to bear a specific function. And if they do and the function is damaged and breaks down , those molecules neither "care" that they cease bearing that function. The very concepts of proofreading and repair implies goal-orientation and "know-how" to keep something working and going. In cells, in a variety of biochemical processes, when something goes havoc for some reason, there is readily an armada of different error check and repair mechanisms with their "antenna" out to detect errors, and correct them, preventing lethal consequences . How is this not evidence of intended implementation by intelligence to achieve the specific purpose to maintain the complex cell machinery intact and operating properly? In some cases, very complex multi-part machines are involved performing efficient action to keep other complex molecular machinery and systems outside their own structural needs functional. They operate like fire-men that are called to cease a fire and rebuild the damaged part of the house ( photosystem II). Or a computer technician is called to repair a hard disk ( DNA ) Or a mechanic that is called to repair a 3D printer ( ribosome). But in contrast to human intervention, this biomolecular machinery is preprogrammed to know beforehand exactly when something is not working properly, and is able to work like a roboter and with the precision similar to a surgeon.
The process of gene expression is critical to all life-forms. No life-form could/would survive without these advanced mechanisms in place right from the beginning, when life started. In the pathway from Genes to proteins, and even post-translation, there are many sources of errors - and they must be fixed. Erroneous protein synthesis is due to any disruption in the conversion of the informational nucleotide sequence stored in DNA into a functioning protein. Besides amino-acid misincorporations, sources of errors are transcription errors, aberrant splicing, premature termination, faulty posttranslational modifications, and kinetic missteps during folding. This definition explicitly includes correctly synthesized polypeptides that fail to fold into a functional protein.Translation is the most error-prone step of protein synthesis.
The act of anticipation — foresight — is not a characteristic of blind material processes. It is an act of intelligence, of a mind.
DNA and RNA error checking and repair, amazing evidence of design
Error detection and repair during the biogenesis & maturation of the ribosome, tRNA's, Aminoacyl-tRNA synthetases, and translation: by chance, or design?