Overwhelming evidence of Design in Molecular Biology
Thanks to Philip Cunningham
Overwhelming evidence of Design in Molecular Biology?
Biochemical Pathway Maps
http://web.expasy.org/cgi-bin/pathways/show_thumbnails.pl
I showed that particular biochemical pathway chart to a Darwinist once when he asked me for ANY evidence of intelligent design in biology. His response upon seeing it was something along the lines of, ‘Just because it is horrendously complex does not prove it was designed.’. ,,, Well maybe so, but such ‘horrendous complexity’ certainly does not give comfort to the notion that such ‘horrendous complexity’ can be the accumulation of random genetic accidents either!
Here is a ‘horrendously complex’ metabolic pathway chart:
Map Of Major Metabolic Pathways In A Cell – Diagram
http://www.sigmaaldrich.com/img/assets/4202/MetabolicPathways_6_17_04_.pdf
Part of the ‘horrendous complexity’ inherent in metabolic pathways is gone over here:
The 10 Step Glycolysis Pathway In ATP Production: An Overview – video
https://www.youtube.com/watch?v=8Kn6BVGqKd8
At the 6:00 minute mark of the following video, Chris Ashcraft, PhD – molecular biology, gives us an overview of the Citric Acid Cycle, which is, after the 10 step Glycolysis Pathway, also involved in ATP production:
Evolution vs ATP Synthase – Molecular Machine – video
http://www.metacafe.com/watch/4012706
Glycolysis and the Citric Acid Cycle: The Control of Proteins and Pathways – Cornelius Hunter – July 2011
http://darwins-god.blogspot.com/2011/07/glycolysis-and-citric-acid-cycle.html
Moreover, the ATP molecular machine (which is found at the bottom of the metabolic pathway chart) is found to be 100% efficient:
Thermodynamic efficiency and mechanochemical coupling of F1-ATPase – 2011
Excerpt:F1-ATPase is a nanosized biological energy transducer working as part of FoF1-ATP synthase. Its rotary machinery transduces energy between chemical free energy and mechanical work and plays a central role in the cellular energy transduction by synthesizing most ATP in virtually all organisms.,,
Our results suggested a 100% free-energy transduction efficiency and a tight mechanochemical coupling of F1-ATPase.
http://www.pnas.org/content/early/2011/10/12/1106787108.short?rss=1
As well, metabolic pathways in general are found to be ‘optimal’:
Metabolism: A Cascade of Design
Excerpt: A team of biological and chemical engineers wanted to understand just how robust metabolic pathways are. To gain this insight, the researchers compared how far the errors cascade in pathways found in a variety of single-celled organisms with errors in randomly generated metabolic pathways. They learned that when defects occur in the cell’s metabolic pathways, they cascade much shorter distances than when errors occur in random metabolic routes. Thus, it appears that metabolic pathways in nature are highly optimized and unusually robust, demonstrating that metabolic networks in the protoplasm are not haphazardly arranged but highly organized.
http://www.reasons.org/metabolism-cascade-design
Making the Case for Intelligent Design More Robust
Excerpt: ,,, In other words, metabolic pathways are optimized to withstand inevitable concentration changes of metabolites.
http://www.reasons.org/making-case-intelligent-design-more-robust
Such 100% efficiency and optimality being found in molecular biology is hard (impossible?) to explain on Darwinism given what was revealed in a paper that came out yesterday:
Study demonstrates evolutionary ‘fitness’ not the most important determinant of success – February 7, 2014 – with illustration
An illustration of the possible mutations available to an RNA molecule. The blue lines represent mutations that will not change its function (phenotype), the grey are mutations to an alternative phenotype with slightly higher fitness and the red are the ‘fittest’ mutations. As there are so few possible mutations resulting in the fittest phenotype in red, the odds of this mutation are a mere 0.15%. The odds for the slightly fitter mutation in grey are 6.7% and so this is far more likely to fix, and thus to be found and survive, even though it is much less fit than the red phenotype.,,,
By modelling populations over long timescales, the study showed that the ‘fitness’ of their traits was not the most important determinant of success. Instead, the most genetically available mutations dominated the changes in traits. The researchers found that the ‘fittest’ simply did not have time to be found, or to fix in the population over evolutionary timescales.
http://phys.org/news/2014-02-evolutionary-important-success.html
This headline sums up the preceding finding very nicely:
Fittest Can’t Survive If They Never Arrive – February 7, 2014
http://crev.info/2014/02/fittest-cant-survive-if-they-never-arrive/
Moreover, as if that were not ‘horrendously’ bad enough for Darwinists, metabolic pathways are found to operate on ‘Quarter Power Scaling’. i.e. Metabolic Pathways operate as if they were ‘four-dimensional’
Kleiber’s law
Excerpt: Kleiber’s law,[1] named after Max Kleiber’s biological work in the early 1930s, is the observation that, for the vast majority of animals, an animal’s metabolic rate scales to the 3/4 power of the animal’s mass.
http://en.wikipedia.org/wiki/Kleiber%27s_law
4-Dimensional Quarter Power Scaling In Biology – video
http://www.metacafe.com/w/5964041/
Jerry Fodor and Massimo Piatelli-Palmarini put the problem that Quarter Power Scaling presents to Darwinism this way:
“Although living things occupy a three-dimensional space, their internal physiology and anatomy operate as if they were four-dimensional. Quarter-power scaling laws are perhaps as universal and as uniquely biological as the biochemical pathways of metabolism, the structure and function of the genetic code and the process of natural selection.,,, The conclusion here is inescapable, that the driving force for these invariant scaling laws cannot have been natural selection.”
Jerry Fodor and Massimo Piatelli-Palmarini, What Darwin Got Wrong (London: Profile Books, 2010), p. 78-79
The reason why ’4-Dimensional’ metabolic pathways are impossible for Darwinism to explain is that Natural Selection operates on the 3-Dimensional phenotypes. ’4-Dimensional’ metabolic pathways are simply ‘invisible’ to natural selection. The fact that 4-Dimensional things are completely invisible to 3-Dimensional things is best illustrate by ‘flatland’:
Flatland – 3D to 4D shift – Carl Sagan – video
https://www.youtube.com/watch?v=UnURElCzGc0
Quote, Verse and Music:
“Geometry is unique and eternal, a reflection from the mind of God. That mankind shares in it is because man is an image of God.”
– Johannes Kepler
Romans 1:20
For since the creation of the world His invisible attributes are clearly seen, being understood by the things that are made, even His eternal power and Godhead, so that they are without excuse,
Unto The King Eternal – music
https://www.youtube.com/watch?v=mLPYRhOQcCU
Thanks to Philip Cunningham
Overwhelming evidence of Design in Molecular Biology?
Biochemical Pathway Maps
http://web.expasy.org/cgi-bin/pathways/show_thumbnails.pl
I showed that particular biochemical pathway chart to a Darwinist once when he asked me for ANY evidence of intelligent design in biology. His response upon seeing it was something along the lines of, ‘Just because it is horrendously complex does not prove it was designed.’. ,,, Well maybe so, but such ‘horrendous complexity’ certainly does not give comfort to the notion that such ‘horrendous complexity’ can be the accumulation of random genetic accidents either!
Here is a ‘horrendously complex’ metabolic pathway chart:
Map Of Major Metabolic Pathways In A Cell – Diagram
http://www.sigmaaldrich.com/img/assets/4202/MetabolicPathways_6_17_04_.pdf
Part of the ‘horrendous complexity’ inherent in metabolic pathways is gone over here:
The 10 Step Glycolysis Pathway In ATP Production: An Overview – video
https://www.youtube.com/watch?v=8Kn6BVGqKd8
At the 6:00 minute mark of the following video, Chris Ashcraft, PhD – molecular biology, gives us an overview of the Citric Acid Cycle, which is, after the 10 step Glycolysis Pathway, also involved in ATP production:
Evolution vs ATP Synthase – Molecular Machine – video
http://www.metacafe.com/watch/4012706
Glycolysis and the Citric Acid Cycle: The Control of Proteins and Pathways – Cornelius Hunter – July 2011
http://darwins-god.blogspot.com/2011/07/glycolysis-and-citric-acid-cycle.html
Moreover, the ATP molecular machine (which is found at the bottom of the metabolic pathway chart) is found to be 100% efficient:
Thermodynamic efficiency and mechanochemical coupling of F1-ATPase – 2011
Excerpt:F1-ATPase is a nanosized biological energy transducer working as part of FoF1-ATP synthase. Its rotary machinery transduces energy between chemical free energy and mechanical work and plays a central role in the cellular energy transduction by synthesizing most ATP in virtually all organisms.,,
Our results suggested a 100% free-energy transduction efficiency and a tight mechanochemical coupling of F1-ATPase.
http://www.pnas.org/content/early/2011/10/12/1106787108.short?rss=1
As well, metabolic pathways in general are found to be ‘optimal’:
Metabolism: A Cascade of Design
Excerpt: A team of biological and chemical engineers wanted to understand just how robust metabolic pathways are. To gain this insight, the researchers compared how far the errors cascade in pathways found in a variety of single-celled organisms with errors in randomly generated metabolic pathways. They learned that when defects occur in the cell’s metabolic pathways, they cascade much shorter distances than when errors occur in random metabolic routes. Thus, it appears that metabolic pathways in nature are highly optimized and unusually robust, demonstrating that metabolic networks in the protoplasm are not haphazardly arranged but highly organized.
http://www.reasons.org/metabolism-cascade-design
Making the Case for Intelligent Design More Robust
Excerpt: ,,, In other words, metabolic pathways are optimized to withstand inevitable concentration changes of metabolites.
http://www.reasons.org/making-case-intelligent-design-more-robust
Such 100% efficiency and optimality being found in molecular biology is hard (impossible?) to explain on Darwinism given what was revealed in a paper that came out yesterday:
Study demonstrates evolutionary ‘fitness’ not the most important determinant of success – February 7, 2014 – with illustration
An illustration of the possible mutations available to an RNA molecule. The blue lines represent mutations that will not change its function (phenotype), the grey are mutations to an alternative phenotype with slightly higher fitness and the red are the ‘fittest’ mutations. As there are so few possible mutations resulting in the fittest phenotype in red, the odds of this mutation are a mere 0.15%. The odds for the slightly fitter mutation in grey are 6.7% and so this is far more likely to fix, and thus to be found and survive, even though it is much less fit than the red phenotype.,,,
By modelling populations over long timescales, the study showed that the ‘fitness’ of their traits was not the most important determinant of success. Instead, the most genetically available mutations dominated the changes in traits. The researchers found that the ‘fittest’ simply did not have time to be found, or to fix in the population over evolutionary timescales.
http://phys.org/news/2014-02-evolutionary-important-success.html
This headline sums up the preceding finding very nicely:
Fittest Can’t Survive If They Never Arrive – February 7, 2014
http://crev.info/2014/02/fittest-cant-survive-if-they-never-arrive/
Moreover, as if that were not ‘horrendously’ bad enough for Darwinists, metabolic pathways are found to operate on ‘Quarter Power Scaling’. i.e. Metabolic Pathways operate as if they were ‘four-dimensional’
Kleiber’s law
Excerpt: Kleiber’s law,[1] named after Max Kleiber’s biological work in the early 1930s, is the observation that, for the vast majority of animals, an animal’s metabolic rate scales to the 3/4 power of the animal’s mass.
http://en.wikipedia.org/wiki/Kleiber%27s_law
4-Dimensional Quarter Power Scaling In Biology – video
http://www.metacafe.com/w/5964041/
Jerry Fodor and Massimo Piatelli-Palmarini put the problem that Quarter Power Scaling presents to Darwinism this way:
“Although living things occupy a three-dimensional space, their internal physiology and anatomy operate as if they were four-dimensional. Quarter-power scaling laws are perhaps as universal and as uniquely biological as the biochemical pathways of metabolism, the structure and function of the genetic code and the process of natural selection.,,, The conclusion here is inescapable, that the driving force for these invariant scaling laws cannot have been natural selection.”
Jerry Fodor and Massimo Piatelli-Palmarini, What Darwin Got Wrong (London: Profile Books, 2010), p. 78-79
The reason why ’4-Dimensional’ metabolic pathways are impossible for Darwinism to explain is that Natural Selection operates on the 3-Dimensional phenotypes. ’4-Dimensional’ metabolic pathways are simply ‘invisible’ to natural selection. The fact that 4-Dimensional things are completely invisible to 3-Dimensional things is best illustrate by ‘flatland’:
Flatland – 3D to 4D shift – Carl Sagan – video
https://www.youtube.com/watch?v=UnURElCzGc0
Quote, Verse and Music:
“Geometry is unique and eternal, a reflection from the mind of God. That mankind shares in it is because man is an image of God.”
– Johannes Kepler
Romans 1:20
For since the creation of the world His invisible attributes are clearly seen, being understood by the things that are made, even His eternal power and Godhead, so that they are without excuse,
Unto The King Eternal – music
https://www.youtube.com/watch?v=mLPYRhOQcCU
