Intelligent Design, the best explanation of Origins

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Intelligent Design, the best explanation of Origins » Molecular biology of the cell » Metabolism » Metabolism and Catabolism - evidence of design

Metabolism and Catabolism - evidence of design

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Recycling, and the orchestration of anabolism and catabolism, evidence of natural forces, or design?

Recycling or reuse of used material, organized decomposition into basic building blocks, separation, and organized re-use is an exclusive activity performed by intelligence, namely by us, humans, who have figured out of know-how. And the more we practice it, the more sustainable our and less destructive our activities are for the planet where we live in.

In biological cells, recycling is a highly orchestrated, complex, and coordinated process. It is called catabolism. While in anabolism, metabolic networks construct molecules from smaller units, while in catabolism, a set of metabolic pathways breaks down molecules into smaller units that are either oxidized to release energy or used in other anabolic reactions       Interestingly, anabolism and catabolism occur simultaneously in the cell. The conflicting demands of concomitant catabolism and anabolism are managed by cells in two ways. First, the cell maintains tight and separate regulation of both catabolism and anabolism, so metabolic needs are served in an immediate and orderly fashion. Second, competing metabolic pathways are often localized within different cellular compartments. Isolating opposing activities within distinct compartments, such as separate organelles, avoids interference between them.

Question: How could unguided, random, not goal oriented processes on early earth have brought this situation and matter of facts into being?  regulation, order, management, organized separation, compartmentalization are known to be exclusively brought into action by intelligence. No exception is known.

A rather limited collection of simple precursor molecules is sufficient to provide for the biosynthesis of virtually any cellular constituent, be it protein, nucleic acid, lipid, or polysaccharide.Certain of the central pathways of intermediary metabolisms, such as the citric acid cycle, and many metabolites of other pathways have dual purposes—they serve in both catabolism and anabolism. Remarkably, the opposite metabolic directions is that such pathways must be independently regulated.

Question: How could such regulation have emerged in a stepwise, slow, gradual trial and error fashion, and the fact that regulation is essential? Could and would both independent regulation implementation not have had to emerge simultaneously, if considered, that the reverse cycle is slightly different and differently adjusted in order to work properly?

If catabolism and anabolism passed along the same set of metabolic tracks, equilibrium considerations would dictate that slowing the traffic in one direction by inhibiting a particular enzymatic reaction would necessarily slow traffic in the opposite direction. Independent regulation of anabolism and catabolism can be accomplished only if these two contrasting processes move along different routes or, in the case of shared pathways, the rate-limiting steps serving as the points of regulation are catalyzed by enzymes that are unique to each opposing sequence.

It is evident that in order to implement such a system that works both ways, there must be foresight and the setting of specific goals, and teleology, which is what naturalism must try to avoid to be true.

The spatial compartmentalization of metabolic pathways within cells provides important advantages, one of which is isolating competing pathways from one another. Cells and organisms also exhibit temporal compartmentalization of their metabolic pathways. That is, metabolic pathways may be turned on and off in a time-dependent and/or cyclic fashion. For example, the metabolism of many organisms—microbes, animals, and plants—is regulated in synchrony with the 24-hour cycle of day and night, a pattern called circadian rhythmicity and often referred to as the biological clock.

Question: How could such a circadian rhythm have emerged in a random manner? It could not be explained by evolution since: 

" The 24-hour circadian clock found in human cells is the same as that found in algae and dates back millions of years to early life on Earth, and is linked to DNA and gene activity "

and: " Because light and/or varying nutrient availability represent key signals regarding the transitory nature of the environment, and organisms have evolved and adapted to exploit the information in such signals. ".

Remarkably, there is not only a 24h circadian clock, but also a 7-day Circadian Clock, which coincides with Gods setup of six days, and the Sabbath, the rest on the seventh day:

The seven day Circadian Rhythms: "Nature's Intricate Clockwork"

Metabolic networks are extraordinarily complex. The Human Metabolomics Database ( provides data on more than over 40,000 metabolites in cells and fluids (blood, urine, and so on) of the human body. The metabolomes of plants are even more complex, with estimates suggesting hundreds of thousands of different metabolites across the plant kingdom. Metabolomic assays must be able to resolve and discriminate this extraordinary array
of small molecules.

Atheists can tell me as much and as often as they want , that i lack credulity towards their narrative, that such complex molecular networks could have emerged randomly on early Earth. I will grant them with the same return: It requires a lot of faith / credulity that such complexity could be the process of random chemical interaction on a prebiotic earth.

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